A previous OPIGlet discussed biscuits in his blog post.
Not to be outdone, I will now discuss something even more nerdy: new avenues for comic book adapations. For brevity’s sake, this OPIGlet will focus on the DC and Marvel Corporations as key examples.1
Category Archives: Group Meetings
Journal Club: Is our data biased, and should it be?

Last week I presented the above paper at group meeting. While a little different from a typical OPIG journal club paper, the data we have access to almost certainly suffers from the same range of (possible) biases explored in this paper.
Continue readingThings I’ve Learned from Hosting Speaker Events
For the past couple of years I’ve been involved in running the Oxford University Scientific Society. We host weekly talks in Oxford during the Undergraduate Term, inviting speakers from all scientific disciplines to come and discuss their field with our members. Here are four important lessons I’ve learned from being involved!
Comparative analysis of the CDR loops of antigen receptors
Allow me to present our recently accepted paper: Comparative analysis of the CDR loops of antigen receptors, to appear in Frontiers in Immunology [1]. In the blog post I will give a quick five-minute summary of the key messages in this work.
Continue readingA collection of prion factoids
It’s been several years since I last presented a talk on prions to OPIG, so I thought a neat way of getting up to date would be to read “The prion 2018 round tables“. What’s the current understanding and are we any closer to determining a structure of PrPSc?
Continue readingWhen OPIGlets leave the office
Hi everyone,
My blogpost this time around is a list of conferences popular with OPIGlets. You are highly likely to see at least one of us attending or presenting at these meetings! I’ve tried to make it as exhaustive as possible (with thanks to Fergus Imrie!), listing conferences in upcoming chronological order.
(Most descriptions are slightly modified snippets taken from the official websites.)
OpenMM – easy to learn, highly flexible molecular dynamics in Python
When I came to OPIG this past March I realized I had a novel opportunity – there was no one to tell me which molecular dynamics (MD) program I had to use! Usually, researchers do not have much choice in the matter due to a number of practical concerns. Conflicts between input and output file formats, forces, velocities, and basically everything else between MD suites make having multiple programs flying around tenuous at best if you want group members to be able to help one another. After weighing my options, I settled on OpenMM – and so far I am very happy with the decision.
Custom coffee mugs for OPIG
As of last week, many members of OPIG have custom mugs. Each comes with an illustration of its owner’s favourite protein, as well as, the OPIG logo. There is an additional `unofficial’ OPIG logo on the backstamp (the outside bottom).
Continue readingGene-Edited Crops


Two Tools for Systematically Compiling Ensembles of Protein Structures
In order to know how a protein works, we generally want to know its 3-dimensional structure. We then can either try to solve it ourselves (which requires considerable time, skill, and resources), or look for it in the Protein Data Bank, in case it has already been solved. The vast majority of structures in the Protein Data Bank (PDB) are solved through protein crystallography, and represent a “snapshot” of the conformational space available to our protein of interest. Continue reading