Author Archives: Henriette Capel

SAbDab2: The structural antibody database in the age of machine learning 

Henriette L. Capel, Odysseas Vavourakis, Benjamin H. Williams, Christopher R. Taylor, and Charlotte M. Deane

The Structural Antibody Database 

The Structural Antibody Database (SAbDab) [1] is a publicly available repository of experimentally determined antibody structures, first released in 2013. Explicit support for single-domain antibodies was added in 2021, with SAbDab-nano [2]. Detailed annotations and consistent maintenance have made SAbDab a central resource supporting important advances in the field. SAbDab has been used to study antibody-antigen interactions, including SARS-CoV-2; to predict antibody structure; to design antibodies de-novo; and to investigate antibody flexibility. 

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