Currently I’m working on developing a new strategy to use FREAD within the ABodyBuilder pipeline. While running some tests I’ve realised that some of the RMSD values that there were some minor miscalculations of CDR loops’ RMSD in my paper.
To start with, the main message of the paper remains the same; the overall quality of the models (Fv RMSD) was correct, and still is. ABodyBuilder isn’t necessarily the most accurate modelling methodology per se, but it’s unique in its ability to estimate RMSD. ABodyBuilder would still be capable of doing this calculation regardless of what the CDR loops’ RMSD may be. This is because the accuracy estimation looks at the RMSD data and places a probability that a new model structure would have some RMSD value “x” (given the CDR loop’s length). Our website has now been updated in light of these changes too.