{"id":8279,"date":"2022-06-08T12:14:31","date_gmt":"2022-06-08T11:14:31","guid":{"rendered":"https:\/\/www.blopig.com\/blog\/?p=8279"},"modified":"2022-06-14T17:39:53","modified_gmt":"2022-06-14T16:39:53","slug":"antibodies-as-drugs-keystone-symposia","status":"publish","type":"post","link":"https:\/\/www.blopig.com\/blog\/2022\/06\/antibodies-as-drugs-keystone-symposia\/","title":{"rendered":"Antibodies as Drugs: Keystone Symposia"},"content":{"rendered":"\n

Between the 27th April and 1st of May, I was very fortunate to be able attend the Antibodies as Drugs Keystone Symposium and give my first conference talk internationally, in which I spoke about the methods our group has developed for using structure to make predictions about where an antibody binds relative to other antibodies. This included paratyping [1], Ab-Ligity [2] and most recently SPACE [3].<\/p>\n\n\n\n

I will preface this by saying that lots of the work people spoke about was unpublished, which was so exciting, but makes for a difficult blog post to write. To avoid any possibility of putting my foot in my mouth I will keep the science very surface level. The conference was held at the Keystone resort in Colorado, and the science combined with a kind of landscape I have never experienced before made for an extremely cool experience. This meeting was originally combined with a protein design meeting, and the two were split by COVID – this meant that in-silico methods were the minority in the program, but I didn\u2019t mind that as the computational work that was presented was quite diverse so it was definitely a good representation of the field still. I also really enjoyed the large number of infectious disease talks in which we got a good range of the major human pathogens – ebolaviruses, SARS-CoV-2 of course, dengue, hantaviruses, metapneumovirus, HIV, TB and malaria all featured. The bispecific session was another highlight for me. The conference was very well organised and I liked how we were all asked to share a fun fact about ourselves – one speaker shared that he is a Christmas tree farmer in his spare time (I won\u2019t share his name in case he is keeping that under wraps). That made me reconsider how fun I can truly consider myself…<\/p>\n\n\n\n

Without turning this into a travel blog, I also want to add that Keystone was insanely beautiful and make you look at some pics I got. <\/p>\n\n\n\n

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We got to experience snow<\/figcaption><\/figure><\/div>\n\n\n\n\n\n\n\n
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The lake at the centre of Keystone Lodge<\/figcaption><\/figure><\/div>\n\n\n\n

Thank you to the conference organisers and to Charlotte for allowing me to attend and present at such a fantastic meeting.<\/p>\n\n\n\n

[1] Richardson, Eve, et al. “A computational method for immune repertoire mining that identifies novel binders from different clonotypes, demonstrated by identifying anti-pertussis toxoid antibodies.” MAbs<\/em>. Vol. 13. No. 1. Taylor & Francis, 2021.<\/p>\n\n\n\n

[2] Wong, Wing Ki, et al. “Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope.” MAbs<\/em>. Vol. 13. No. 1. Taylor & Francis, 2021.<\/p>\n\n\n\n

[3] Robinson, Sarah A., et al. “Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies.” PLoS computational biology<\/em>17.12 (2021): e1009675.<\/p>\n","protected":false},"excerpt":{"rendered":"

Between the 27th April and 1st of May, I was very fortunate to be able attend the Antibodies as Drugs Keystone Symposium and give my first conference talk internationally, in which I spoke about the methods our group has developed for using structure to make predictions about where an antibody binds relative to other antibodies. […]<\/p>\n","protected":false},"author":58,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","wikipediapreview_detectlinks":true,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"ngg_post_thumbnail":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[466,52,186],"tags":[615],"ppma_author":[540],"class_list":["post-8279","post","type-post","status-publish","format-standard","hentry","category-antibodies","category-conferences","category-immunoinformatics","tag-conference-feedback"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"authors":[{"term_id":540,"user_id":58,"is_guest":0,"slug":"eve","display_name":"Eve Richardson","avatar_url":"https:\/\/secure.gravatar.com\/avatar\/9891300fda41850fb2fc859ef2ee18aae341c49e520511adc5684413cc356ff7?s=96&d=mm&r=g","0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""}],"_links":{"self":[{"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/posts\/8279","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/users\/58"}],"replies":[{"embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/comments?post=8279"}],"version-history":[{"count":3,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/posts\/8279\/revisions"}],"predecessor-version":[{"id":8323,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/posts\/8279\/revisions\/8323"}],"wp:attachment":[{"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/media?parent=8279"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/categories?post=8279"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/tags?post=8279"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/ppma_author?post=8279"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}