{"id":4611,"date":"2019-04-23T12:32:05","date_gmt":"2019-04-23T11:32:05","guid":{"rendered":"https:\/\/www.blopig.com\/blog\/?p=4611"},"modified":"2019-04-29T00:49:55","modified_gmt":"2019-04-28T23:49:55","slug":"more-fun-with-3d-printing","status":"publish","type":"post","link":"https:\/\/www.blopig.com\/blog\/2019\/04\/more-fun-with-3d-printing\/","title":{"rendered":"More Fun With 3D Printing"},"content":{"rendered":"\n<p>Recently the students of the Systems Approaches to Biomedical Science Centre for Doctoral Training took a 2-week module on our favourite subject: structural biology! As part of this, they were given the option to create their very own 3D printed model of a protein.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"625\" height=\"469\" loading=\"lazy\" src=\"https:\/\/i0.wp.com\/www.blopig.com\/blog\/wp-content\/uploads\/2019\/04\/Collage_Fotor.jpg?resize=625%2C469&#038;ssl=1\" alt=\"\" class=\"wp-image-4612\" srcset=\"https:\/\/i0.wp.com\/www.blopig.com\/blog\/wp-content\/uploads\/2019\/04\/Collage_Fotor.jpg?resize=1024%2C768&amp;ssl=1 1024w, https:\/\/i0.wp.com\/www.blopig.com\/blog\/wp-content\/uploads\/2019\/04\/Collage_Fotor.jpg?resize=300%2C225&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.blopig.com\/blog\/wp-content\/uploads\/2019\/04\/Collage_Fotor.jpg?resize=768%2C576&amp;ssl=1 768w, https:\/\/i0.wp.com\/www.blopig.com\/blog\/wp-content\/uploads\/2019\/04\/Collage_Fotor.jpg?resize=624%2C468&amp;ssl=1 624w, https:\/\/i0.wp.com\/www.blopig.com\/blog\/wp-content\/uploads\/2019\/04\/Collage_Fotor.jpg?w=1250&amp;ssl=1 1250w, https:\/\/i0.wp.com\/www.blopig.com\/blog\/wp-content\/uploads\/2019\/04\/Collage_Fotor.jpg?w=1875&amp;ssl=1 1875w\" sizes=\"auto, (max-width: 625px) 100vw, 625px\" \/><\/figure>\n\n\n\n<p>This year we had some great models created, some of which are shown in the picture above. The proteins are (clockwise from top left):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Clathrin (PDB 1XI4) &#8211; a really interesting protein that forms cages around vesicles inside the cell. This one was mine; I wrote about clathrin as part of my undergraduate dissertation many years ago&#8230;<\/li><li>GTPase (PDB 1YZN) &#8211; a protein that can bind and hydrolyse guanosine triphosphate (GTP), involved in membrane trafficking<\/li><li>TAL effector (PDB 3UGM) &#8211; this bacterial protein binds to specific regions of DNA in a host plant to activate the expression of plant genes that aid bacterial infection. The DNA here is in blue, the orange wrapped around it is the protein.<\/li><li>Mechanotransduction ion channel (PDB 5VKQ) &#8211; converts mechanical stimuli into electrical signals in specialized sensory cells.<\/li><li>ATP synthase &#8211; this protein machine builds most of the energy storage molecule ATP, which powers our cellular processes.<\/li><li>DNA (PDB 5F9I) &#8211; a double-helix strand of DNA, 20 base pairs long.<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Recently the students of the Systems Approaches to Biomedical Science Centre for Doctoral Training took a 2-week module on our favourite subject: structural biology! As part of this, they were given the option to create their very own 3D printed model of a protein. This year we had some great models created, some of which [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","wikipediapreview_detectlinks":true,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"ngg_post_thumbnail":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[228],"tags":[230,231],"ppma_author":[515],"class_list":["post-4611","post","type-post","status-publish","format-standard","hentry","category-protein-structure","tag-3d-printing","tag-tangible-models"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"authors":[{"term_id":515,"user_id":24,"is_guest":0,"slug":"claire","display_name":"Claire Marks","avatar_url":"https:\/\/secure.gravatar.com\/avatar\/5d39885b27415e17d14e5aef750a113c6f1713d8e1e40b1cba3bbe123b8c4565?s=96&d=mm&r=g","0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""}],"_links":{"self":[{"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/posts\/4611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/comments?post=4611"}],"version-history":[{"count":2,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/posts\/4611\/revisions"}],"predecessor-version":[{"id":4641,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/posts\/4611\/revisions\/4641"}],"wp:attachment":[{"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/media?parent=4611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/categories?post=4611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/tags?post=4611"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.blopig.com\/blog\/wp-json\/wp\/v2\/ppma_author?post=4611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}