Fragment-based loop modelling pipeline for X-ray crystallography

Fragment-based loop modelling pipeline for X-ray crystallography

Given an incomplete model of a protein, as well as the current electron density map, we apply our loop modelling method FREAD to fill in a gap with many decoy structures. These decoys are then scored using a score based on electron density quality measures computed by EDSTATS. This process can be iterated to arrive at a complete model.

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